Rock, Paper, Sissors

Thinking about this game carefully, one would realize that the chances of winning are about 1 in 3 (33%). Therefor it does not matter which weapon one chooses, becuase each weapon is equal.
However, there are a few strategies to consider before calling a game of Rock, Paper, Sissors (RPS).
For exmaple, if one knows that the person to be challenged has never played before, or has only taken part in the game as a young child, then it would be safe to assume that this person has never really given serious thought about RPS. Therefore, getting into the mind of the novice, one would muse that rock is the most likely choice, because rock seems like a strong weapon regardless of the statistical chance. Also, the weapon is the shape of a fist, which feels aggressive and therefore more powerful. Knowing that a novice is most likely to choose rock, the strategic weapon of choice would then be paper (as paper covers rock).
Of course, if this person seems to have a smirk apon them, then they are probably RPS experts, strategically pretending to be novice. In this case, they would assume that one would assume them novice and throw paper, so the opponent would throw sissor (since sissor cuts paper). In which case rock is the best choice, since rock smashes sissor, and if the opponent does turn out to be novice it would be a draw. In the case of a draw the novice will play sissor (the second most aggressive weapon) or rock again having survived the first round. So rock is again safe to play on one's part.
Of course, it is possible that the expert player knows that you know, and knows that you do not know that they know you know, then they will throw rock to crush one's sissors.
Considering this, no matter what, rock should be thrown. Of course, if one were to always throw rock, then the opponent would know to throw paper, in which case, the best strategy to keep sly would be to throw one's weapons randomly.